The Gunners defeated Blackpool at Bloomfield Road 3-0, while United beat Reading 2-0 at Old Trafford.
The sides' last encounter ended in a 2-2 draw at Old Trafford.
United are in the middle of a seven-game winning run and Arsenal are coming off an impressive 2-0 win against Chelsea.
What time is kick-off?
This match will be held on Friday, January 25.
Kick-off at the Emirates stadium is at 7.55pm.
Is Arsenal vs Manchester United on TV and can I live stream it?
This game will be shown live on BBC One, and you can live stream it on the BBC iPlayer.
Here on SunSport we will as usual be running a dedicated LIVE BLOG from the Emirates Stadium.
How can I watch Arsenal vs Man Utd for free?
BBC One and BBC iPlayer are free for all UK viewers with a TV licence.
Click here to sign up for a licence.
What is the team news?
Arsenal's defensive woes continue as Hector Bellerin has been sidelined potentially for the remainder of the season with a serious knee injury. Danny Welbeck and Rob Holding are both out for the season. Some good news as Henrik Mkhitaryan is back in training after injuring his ankle a month ago.
Man United defenders Chris Smalling and Marcos Rojo are both training again after a foot injury and a knock respectively and could be in contention to face the Gunners. Luke Shaw is sidelined through illness and Marouane Fellaini is out with a calf injury.
What have they said?
Unai Emery [on Solskjaer's Man Utd compared to Mourinho's]: "It's the same players but they are playing with a big performance now. I was watching their last matches and and each player has a lot of confidence, with big performances, and now they are very dangerous."
Solskjaer: "The games against Arsenal were the fiercest battles we had during my time in England. They won the double, we won the treble and the games were just fantastic because they were the two top teams. We had a great team and they had a very good one. It was a special rivalry and I’m not sure the Premier League has seen anything like it since, although perhaps Manchester City and Liverpool at the moment are close."
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