The Belgian striker hobbled off with an ankle injury late-on in the 2-1 win against Arsenal at Old Trafford last weekend.
And the ex-Chelsea striker will be out of the matches against West Ham tomorrow and Watford next Sunday, boss Jose Mourinho has confirmed.
The 24-year-old injured his right ankle, and has already missed United's 1-0 loss at Brighton.
Mourinho said during his press conference today the Red Devils clash against Chelsea is targeted for Lukaku's return.
He said "That's what we try."
Marouane Fellaini is also out of the away trip at the Hammers with a minor muscle injury.
Mourinho added: "He has a muscular problem. Against we try to see if it is possible for the last match."
The Belgian midfielder's future at Old Trafford is unclear at present with his contract up at the end of the campaign.
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