Luis Enrique's men go into the match in Gran Canaria off the back of a 3-2 defeat in the Nations League, and victory for either of their fellow Group A4 sides will see them knocked off top spot.
When does Spain vs Bosnia kick off?
This match will take place on Sunday, November 18.
It will kick off at 7.45pm.
The game will be held at Estadio Gran Canaria in Las Palmas.
Which TV channel is it on and can I live stream it?
This match will be available on Sky Sports Red Button.
Sky and Virgin Media can use the service by heading to any of the Sky Sports channels and pressing the red button.
Alternatively, you can keep up-to-date with all the action on our dedicated SunSport LIVE BLOG.
What is the team news?
Luis Enrique will have a full-strength squad in Gran Canaria with possible debuts for Mario Hermoso and Brais Mendez.
Chelsea's Alvaro Morata could also get a start, having come on as substitution against Croatia.
Bosnia are also injury-free from their 0-0 draw against Austria, with Edin Dzeko expected to be awarded cap number 99 in Spain.
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