The Belfast boxer, who has also won titles at super-bantamweight, is the heavy favourite with a record of one defeat in 27 fights.
What time are the ring walks?
The British pair will go head-to-head at the Manchester Arena TONIGHT
They are the last on a 12-fight card.
Warrington and Frampton will likely begin their ring walks at 10pm.
Which TV channel is it on?
BT Sport Box Office hold the rights to this world title fight, along with a host of exciting undercard bouts.
It will set you back £19.95 to watch the pay-per-view event, with the likes of Billy Joe Saunders and Tommy Fury also fighting.
You can catch it on BT TV, Sky or Virgin Media.
Can I live stream it?
You can also watch the fight online at BT Sport.
It will also be shown live on the BT Sport Box Office app which you can find on mobile or on your tablet.
Alternatively, you can keep up-to-date with our round-by-round SunSport LIVE BLOG.
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