{"id":222077,"date":"2023-09-07T16:00:44","date_gmt":"2023-09-07T16:00:44","guid":{"rendered":"https:\/\/allworldreport.com\/?p=222077"},"modified":"2023-09-07T16:00:44","modified_gmt":"2023-09-07T16:00:44","slug":"human-kidneys-grown-inside-pigs-in-world-first-paving-the-way-for-new-era-of-animal-to-human-organ-transplants-the-sun","status":"publish","type":"post","link":"https:\/\/allworldreport.com\/lifestyle\/human-kidneys-grown-inside-pigs-in-world-first-paving-the-way-for-new-era-of-animal-to-human-organ-transplants-the-sun\/","title":{"rendered":"'Human kidneys' grown inside pigs in world first – paving the way for new era of animal-to-human organ transplants | The Sun"},"content":{"rendered":"

SCIENTISTS have grown near-human kidneys in pigs for the first time.<\/p>\n

The \u201cchimera\u201d organs \u2014 made up of a mixture of human and pig cells \u2014 survived for 28 days inside the animal, Chinese researchers said.<\/p>\n

<\/p>\n

They could pave the way for fully-human organs needed for transplants being grown in pigs in future, helping to meet overwhelming demand.<\/p>\n

Dr Liangxue Lai, of Wuyi University, said: \u201cRat organs have been produced in mice, and mouse organs have been produced in rats.<\/p>\n

\u201cBut previous attempts to grow human organs in pigs have not succeeded.<\/p>\n

\u201cOur approach improves the integration of human cells into recipient tissues and allows us to grow human organs in pigs.\u201d<\/p>\n

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Around 5,000 Brits currently need transplants because they are living with the late stages of deadly kidney disease.<\/p>\n

However the average wait time takes two to three years because not enough kidneys are available, with around 1,100 operations performed a year.<\/p>\n

The delay is too long for many patients, with 45,000 Brits dying of chronic kidney disease annually. <\/p>\n

The new research, published in Cell Stem Cell, sought to address this issue by looking at a new way of getting human organs that doesn\u2019t rely on donors.<\/p>\n

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Researchers took human stem cells \u2014 which can turn into any cell in the body \u2014 and put them into pig embryos.<\/p>\n

These cells caused the embryos to develop human-like kidneys rather than their normal organs.<\/p>\n

The embryos were implanted into surrogate pig mothers, where they developed for four weeks before being taken out to see how the organs fared.<\/p>\n

Five embryos had developed structurally normal kidneys that were made up of up to 60 per cent human cells.<\/p>\n

The researchers said they may be able to develop a fully human kidney in a pig in the future.<\/p>\n

Dr Miguel Esteban, of Guangzhou Institutes of Biomedicine and Health, said: \u201cWe would probably need to engineer the pigs in a much more complex way.<\/p>\n

\u201cThat also brings some additional challenges.\u201d<\/p>\n

Independent experts praised the \u201cpioneering\u201d research, saying it could prove to be the \u201cultimate solution\u201d to the need for more organ transplants.<\/p>\n

Professor Darius Widera, of the University of Reading, said: \u201cIn the future, this technology could address the current shortage of compatible donors for kidney transplantation.\u201d<\/p>\n

Source: Read Full Article<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

SCIENTISTS have grown near-human kidneys in pigs for the first time. 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